NMDA Glutamate Receptor Antagonism and the Heritable Risk for Alcoholism: New Insights from a Study of Nitrous Oxide
نویسندگان
چکیده
Departments of Psychiatry and Neuroscience, Yale University School of Medicine, New Haven, Connecticut (Drs Krystal, Petrakis, O’Malley, Krishnan-Sarin, Pearlson, and Yoon); Psychiatry Services, VA Connecticut Healthcare System, West Haven, Connecticut (Drs Krystal, Petrakis, and Yoon); Behavioral Health Services, Yale-New Haven Hospital, New Haven, Connecticut (Drs Krystal, Petrakis, and Yoon); Olin Center for Neuropsychiatry Research, Institute of Living, Hartford, Connecticut (Dr Pearlson).
منابع مشابه
Effect of acute exposure to ethanol on distribution of NR1 subunit of NMDA receptor of glutamate in cerebral cortex of chick embryo
Introduction: There is considerable evidence that glutamate-mediated excitatory neurotransmission plays an important role in mediating the behavioral actions of acutely administered ethanol. The aim of the present study was to investigate the effect of acute ethanol exposure on NR1 subunit of NMDA (n-methyl-d-aspartate) receptor distribution in the cerebral cortex of chick embryo on the 10th...
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Both glutamate receptors and transporters are known to be important in the postsynaptic regulation of glutamate neurotransmission. However, the maturation profile of glutamate transporter EAAC1 and glutamate receptor subunits (NR1, NR2A and NR2B; and GluR 1-4) in functionally activated saccule-related vestibular nuclear neurons of postnatal rats remains unclear. In the present study, conscious ...
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Both glutamate receptors and transporters are known to be important in the postsynaptic regulation of glutamate neurotransmission. However, the maturation profile of glutamate transporter EAAC1 and glutamate receptor subunits (NR1, NR2A and NR2B; and GluR 1-4) in functionally activated saccule-related vestibular nuclear neurons of postnatal rats remains unclear. In the present study, conscious ...
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